Research & Publications

Scientific Foundation

Explore the peer-reviewed research and scientific evidence supporting Ceragenin technology and its potential to address antimicrobial resistance.

200+
Published Studies
25+
Years of Research
50+
Research Partners
Active Research

Research Focus Areas

Our research spans multiple therapeutic areas, all united by the goal of developing effective solutions for antimicrobial resistance.

Active Research

Antimicrobial Resistance

Investigating how Ceragenins combat drug-resistant pathogens including MRSA, VRE, and multi-drug resistant gram-negative bacteria.

Active Research

Biofilm Disruption

Studying the ability of Ceragenins to penetrate and disrupt protective biofilm matrices that shield pathogens from conventional treatments.

Phase 2

Antifungal Activity

Exploring efficacy against a broad spectrum of fungal pathogens, including Candida and Aspergillus species.

Phase 1

Wound Healing

Evaluating the role of Ceragenins in promoting wound healing while preventing infection in diabetic foot ulcers and other chronic wounds.

Preclinical

Anti-Inflammatory

Investigating the immunomodulatory properties of Ceragenins and their potential to reduce inflammation in infected tissues.

Ongoing

Mechanism Studies

Deep analysis of membrane disruption mechanisms and understanding why resistance development is evolutionarily unfavorable.

Evidence

Ceragenins Are Proven

Extensive research demonstrates broad-spectrum efficacy against bacteria, viruses, and fungi, including drug-resistant strains.

Antibacterial

  • Effective against MRSA (Methicillin-resistant Staphylococcus aureus)
  • Effective against CRE (Carbapenem-resistant Enterobacteriaceae)
  • Effective against ESBL (Extended-spectrum beta-lactamase producing bacteria)
  • Effective against VRE (Vancomycin-resistant Enterococci)
  • Effective against Drug-Resistant Gonorrhea

Antiviral

  • Effective against HIV
  • Effective against Type I & II Herpes
  • Effective against Herpes Zoster

Antifungal

  • Effective against fungi including Candida auris

Key Benefits

No Resistance Development

Ceragenins do not engender resistance due to their unique membrane-targeting mechanism

Accelerated Healing

Proven to accelerate wound healing and tissue repair

Proven Safety

Studied in hundreds of animals and dozens of humans with excellent safety profile

Biomimetic Design

Mimic Cathelicidins like LL-37, natural antimicrobial peptides of the innate immune system

Stable & Scalable

Designed for stability and scalable manufacturing for commercial applications

Peer-Reviewed Research

Key Publications

Our technology is backed by extensive peer-reviewed research published in leading scientific journals.

CSA-44 Biofilm Research

PubMed2022Biofilm prevention and reduction

Ceragenin CSA-13 UTI Study

Nature Scientific Reports2022Urinary tract infection treatment

Ceragenins Antifungal Activities

PubMed2018Antifungal efficacy

Access our complete publication database on PubMed

View All Publications on PubMed